If you are looking for a NFL Week 5 betting preview with picks and predictions for the Sunday Night Football Primetime Kansas City Chiefs vs Jacksonville Jaguars matchup, we have you covered! Our NFL handicapping experts discuss this matchup from a sports betting perspective, sharing their picks and predictions vs. the current odds.
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🏈 NFL Week 5 – October 5, 2025
Kansas City Chiefs vs. Jacksonville Jaguars
Location: EverBank Stadium, Jacksonville, FL
Kickoff: 8:15 PM ET
TV: ABC / ESPN
Current Spread & Total: Chiefs -3.5, Over/Under 46.5
Team Hashtags: #ChiefsKingdom #DUUUVAL
🏈 Team Highlights
Kansas City Chiefs
Record: 2–2
Quarterback Patrick Mahomes has been named AFC Offensive Player of the Week following a stellar performance against the Baltimore Ravens.
Tight end Travis Kelce is set to reach a significant milestone on his 36th birthday.
Jacksonville Jaguars
Record: 3–1
Defensive end Travon Walker recently underwent wrist surgery but could potentially play against the Chiefs.
The Jaguars’ defense has forced 13 turnovers this season, matching the 2018 Browns for the most over the first four games in a decade.
📌 Follow the Teams on Twitter
@Chiefs
@Jaguars
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